SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '164d36c54d02fecdbd0ed76b90c618e54e7eefcece07e57b9628fc67602f99b4' 
  AND token = 'ClAjx40XGfBKheWiGXWinIHKC+c6RG1CxzsEmze1bPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}