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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '061e41c7108dff2be071c096c89f8f8f5a076a9d00c612d5288228d3924a58cf' 
  AND token = 'sUpSLpQTTq3GiQrCYdQsuHD3XJXHlKqGQz7bA71VyFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}