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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ee439e4d523b00236bf1538823d05e5ddee16938d6e6d94d586c561286b1616' 
  AND token = 'HHG/ARFKetX5oz2olI9YC3Sg4wQjLMRTcVWvGpj/T2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}