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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427dd705b276d544bac66a86a80e3a6cf88075bc675fb23b3446fd89093fcba1' 
  AND token = 'GWNSBE9+hMHAbgG7LTtA+vvUhfBa6bhMGDWWm/CUl4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}