SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4873fccb101828ce860ae4e7932bbfd4feb940c676f6be79c57d4f00f98a7bf' 
  AND token = 'l8ZmgoQG1eiPOWOho1ivQ3/uRXxbbz4XQW7b4MvMULI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}