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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '994406e423b5d9cb1962e5e8003db3358b22ed162fdfff9e3a3c7e58291c8393' 
  AND token = '8ATH0UXuYv2Ad/Goxgr08T4d5PWbRsVMoP370s7SuE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}