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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d14229c000ae27c74dbd22441a8b519f6ac22c1109080a3fe7698c17b1478a1' 
  AND token = 'wprST1ClU9UtaIjWMl/e21vOdIyZewbBPmhEzffLaw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}