SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c023bf3782bd5ff78c017ecc0abdf8346c995ff65c00b07edafaf03df0bf87a' 
  AND token = 'U/Xh19AiP6/SlwN9P4Tz0sDOybVZ306cvNSYBUEdfHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}