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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f4784c493e33a5c78a7392e1e00bfd00ed232ba87cf979ca9a29993f57cdd30' 
  AND token = '8FurE8Et6lk+RNtUNuVfKRMhv8BcxJ7cUP+J8sCwZo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}