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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d8c483784d5a475b5f90ee80d3ed333432c9cc6877578e8acf28af05f7e46e1' 
  AND token = 'wiN+XI+cc1Sebjpa3Bjz4V5hw8RZeMaiwz+7dFIazaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}