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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dff29d94693459b0f3cfba9492c9a8d761168dcf1bc45a70df8132a6760f2441' 
  AND token = 'nXIwpyxoQFOdzCohckVaoQ1NPcnMnqF2CPBtHY6UwC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}