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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0848be78c48ee9818c0f95d24b0241d51962b02318394cd8f722a322a28b1be' 
  AND token = 'jKumQngs7EadsOZOm6/RFnSOZ9feH0W20EPQDRtA604=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}