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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ace3b440c1aaea5afedd79efda85eb98a46a4e035c11521f88a53f67235a8b' 
  AND token = 'bOQ1J88lJ7BrMXj7easVYbX1fxZVuJn4qVV0wmJtf7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}