SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd053f6db40d400a9a04c4aa8e21fba6c5ca7e27c08dd37125f33d23fdbe02bfc' 
  AND token = 'MneSUd6EdWk4yJH69j1qcgTMN1GpqFFE+pomQ0MzAS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}