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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ce3724a69be9f9772884558cbe46e0e7294a239182a7750065be6d7293be418' 
  AND token = '1JE6S1udVZDe/3T1YDmOXgvF2v6oG8h7vVqVF3A65rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}