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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a969f641d2999919b266d0e44a6a83433b12ed04892512a74f1c9a961170855' 
  AND token = 'TMa3XWe83gam4RCxSm6N6abFswTW0OlkhbiWxVPnlkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}