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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e354eb16f9c666a025f6d37190519ef864b87eca6bd0f63fc82d829b777d1472' 
  AND token = 'nnJYY8tf2eUolUsEZWio5zIrLmiU66YhGyR1fan2M4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}