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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88ad2a0a502bc025ec14019da48b5bd4de2911edfbd609c29a57a5214039c98c' 
  AND token = 'IZ09WbEG9Vapj0U9eYWHJJAEKDKHvNFEOERV0bBBC2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}