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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37fc2e7acd6851644c18a080084c9a4ff4d3003bd77babfbcae0aff5125a3026' 
  AND token = 'wfVemTLQUgYTOAbSTdrFSkDV4JIR9lOKNiqYVGcExMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}