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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7a42978f1c8bd6176d249fb10510eabccba92618b02f17e50651e37b76487ad' 
  AND token = 'mbXMzKtR8PkifT4SBYN170dCTQ4FLA5hMwZ2Xo2GAws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}