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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ae383d81a7d6d4ebad354ed62cc780a6544491a65c8c899003f06c94e505396' 
  AND token = 'FFNnDsZciT7QCZSM6Lq7nmPklwxcEMjOORBpQ/dCanU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}