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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5d36f844d7fccd5e14a03c6163e7364bb50e636968f73cd50993e03586d1f4e' 
  AND token = '6v5DGNDlarg/FvImYVtoELtE1UQ3JM8TZoB8t0C0pdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}