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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2e17eeeecdfeb6f5d8a333af8aed5d9f8d6f842ddd9191b4669824628324d0' 
  AND token = 's5OHMFB+GCgt7HfjWBS8bIOE8XSasAYgx0KDsGUA7tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}