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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36fe89413a19df18a2b2fcf8c8f4e1a87711a84829ceaf256543e2fb6c3a13a5' 
  AND token = 'oI3nXl+gSGIrho7qAx8/ZG76cIfLRtlc3DyanHKRJiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}