SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57b28d14b8b071549ac8340834361f293033c4392b14c6e7fd41845bfae9468d' 
  AND token = 'ViMu+enb/2P8yUI4mTiCXfmdPYAlW0zhHZWfk0oe2uQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}