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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '885dc78d172201f43efc86ad943f7153b4d8e195ecdfc5216a2aca1af55e9a64' 
  AND token = 'nj8Ig8h/1OfKMWLIOly6rt3zEAyqQD9adl9IStK4ZPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}