SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f0d5f8dc81e9511976e14c056176f9b1d5400b3351f131b5d0da9f9f5eab7e6' 
  AND token = 'xGpi3x+vCyLnH39/rrjINdJCc7cbplsTzP7Rvzws1wU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}