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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '413f1f09dfa2c332dfdd4533df99e322da361e642a875e106292cc02587e5c87' 
  AND token = 'DGUb5z9UVwK2MEBRxS4vnvu2u9u0h88A3+2MwYhgg1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}