SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79a79fbfaac2dcf5a9ecce1c7a6c9989572014b68fea6eba313904e801b4b50a' 
  AND token = 'XoEcd7Nqm9/6jJezTJg4fHqfi9RlBtgYxvPGwWWeMfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}