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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0a4d144aacc1ce86ce7dfd7581686cd382172e119f26d8408efc59042a03c34' 
  AND token = 'lOf0CSa58+Qv76LXo1dcqj5yBvjq6AtiZhUl9ks76Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}