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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e647fcc8682058c9fb9c62bcb2c48a8171205f32db853297c670823703bf4daf' 
  AND token = 'QI5/TwokgiRmiSkn0LyBW9ooibjury8OpWDQtFq9ueo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}