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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b373b76047ecc41347153cb1be2200ac243a85eb7f57b73ae5138fac3aa3beeb' 
  AND token = 'bSpwBVxPgKzgZpoOE3nUq8slWIXbe5zak2TfZ/oCWEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}