SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20dd56d960f808b14dc2a369d5bc4557fccfa612794469be5e4503b67eb4db8f' 
  AND token = 'nO6JqkK9wL3uSk4Qpn5fKJB5TyBQ6Bao1680QAbUDZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}