SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1caca017ac5c39cb31ab0178db4054aecd7d9e57d3232b23c72843678ac4fd7' 
  AND token = 'JAmjwjo8WHm3KkcOOyi+SNlrthJ4en+lGNjyT4qM6KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}