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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c236cfc80d91c7619dbce6f5e88cf29e7d55837c3591ce4275f3897d2c5b43b2' 
  AND token = 'SOrunQCG+k2/O7/6t+nx/kDkhMw3AtYe86QY4e1hrwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}