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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da1d12b6fdcad5ef90bc58143ffac55054b021cfe4b507617173728c85b317f' 
  AND token = 'kahBk+f3XtEWWudxa/7mWDi/zA/pgA+uHlc74X1NIOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}