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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e315e8d800780eee24fbd9134f6d8bf0ad70a6d8b64a89803f85eeb155d294c' 
  AND token = 'UdBGd922DWkWTx2tgfCLi7YNHt++MbpT/HZ7rJOmZQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}