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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bba9b8f0241f732ab8b9763eb8d9540bc68b3366bd87dcd4da98d368ee6ad788' 
  AND token = 'Tx/XgTzPNkfg+6KytCOd0xSS+R6IzW6R/wGrTmydSvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}