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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff61ff00f6b97b1b7e53a3d0406a6c8e304f231f781784ee214e1d8750a7dedf' 
  AND token = 'yZCQK0GmyAWsswbvP/Q6jbkcJDznrecYaI7q63A+jCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}