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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26af73a7faea8f16355e8b11a20697d5f47c27bd4e9c802161badbb3ea09e09d' 
  AND token = 'Gaa/Gy0+wSbXmxsX22vCQATdjMbEz+6Ft212wcOVZ5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}