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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c5198a287b7044e854806403114d549020c448bb967880b9f30e802c6b2d64f' 
  AND token = 'NQ5Di3ZzHq0ui7PvsDrfyNjaP1IGv19x5mOb9qsCYe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}