SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e08cca936543d7400ccf587cce8f42b4608647fb8f8b3cc7dc2327ae238eee6' 
  AND token = 'ytAM3ww6i60ViNN8wcTvsQji1RWmPnBhi3z1sOo1pZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}