SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '505979110aa213b8ae0b06d5601b062e8b66b4f9fb2be308c71309013f8f3a21' 
  AND token = 'pCXQ32qos6viuAUIx/gg+N68jKgnIbtWPA1Dz3gUxvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}