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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c596c7dca1a3562d0ce710a09bb3ad8c19716c9304c86c3fce796550caefa18e' 
  AND token = 'uwT5SsHCrJDydR+AcFgp7exU0xnLk059hsuPm7MD1xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}