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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1577f34d41cd9cdb227e15a5341b8c3213adea01a4c2f019d5d8e166353ee1' 
  AND token = 'be9gAwbW0KORQWgu0M1aTRHK3WubyWN5Nozvut2+Fz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}