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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8a71a7f66e0a183fa65e8e3f37987d535463f648279180b1416c0b4270412b' 
  AND token = 'DJHa1i2P75f2Db6+eVS8077Mnbp2d4VNbzESA5UrcHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}