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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3a98c78b4f320ef72feb7a0e7afeee1ccd17cfde56d04d1835125638d16582' 
  AND token = 'gf4GKgt+pOV8JLLpSV6PQ6nNlafPN0JSs0El8mRWhfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}