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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77e81a2167b3446d66e573e64dd5b6689ab2b5214a019ae232b12c18d0690491' 
  AND token = 'YFeUszddfr43qH8VPd3SpSBQtvi5E5Q09Ydy2nGocEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}