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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecca73c4ce7a4d4003e897159517c69087d4fb53fa1849b733a91fe77a17bdce' 
  AND token = 'qnmReYtaif35iTdiVSCs20+hxcFF/Oav6tIPwECR5II=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}