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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b73b0866cd78f4099398ca85c4e0bd99e07ed726a0b112e258e832eab6b94995' 
  AND token = '5D3oOZnKfkmj7gbtpNZaQ5JapJoItcKzdaA9JZWt2tY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}